Tempo is moving toward a new era in tissue engineering with our MAP material science technology. MAP is a core technology based on a scaffold’s physical microenvironment, compatible with any material chemistry, that enables Tempo to create minimally invasive, fully synthetic, and precision-engineered tissue scaffolds that are not rejected by the host immune system and keep local immunity polarized to a type 2 ‘pro-regenerative’ state.
By harnessing the power of immune polarization, MAP rapidly builds new tissue in damaged areas, avoiding scar formation pathways and enabling the regain of function in critical organs. TT101 is a stand-alone material without any cells or biological factors; however, the MAP technology platform can be easily combined with controlled-release technologies for small molecules and stem cells to improve engraftment and therapeutic potential.